Dental Tribune America

Journal of Dental Research’s May issue focuses on oral and head and neck cancer

ALEXANDRIA, Va., U.S.: This year marks the centennial of the Journal of Dental Research (JDR). To celebrate, JDR is featuring a yearlong monthly commemorative article and podcast series that highlights topics that have transformed dental, oral and craniofacial research over the past century. In May, the focus is on oral and head and neck cancer.

Prof. Peter J. Polverini from the University of Michigan and Prof. Mark W. Lingen from University of Chicago discuss the history and future of oral and head and neck cancer in an article titled “A history of innovations in the diagnosis and treatment of oral and head and neck cancer.”

“Historical records as far back as 3000 BCE show that oral and head and neck cancer was a disease process well known to Egyptian physicians,” said Polverini. “During the 20th century, evidence-based medicine catalyzed the development of rigorous science-based diagnostic and treatment protocols. The use of surgery, therapeutic radiation and chemotherapy as single treatment agents, or in combination with one another, has gradually emerged as the preferred approach to cancer therapy.”

In addition to the article, a podcast featuring Polverini and Lingen under the aforementioned title, and moderated by JDR Associate Editor Prof. Jacques E. Nör, covers the topic in further detail.

“New technologies, such as the sequencing of the human genome, metabolomics and proteomics have provided the foundation for what we today call precision medicine,” said Lingen. “The future success of tailored medical treatment for cancer patients will depend on the discovery of new druggable targets with improved therapeutic efficacy. As the precision and sensitivity of existing tools for prevention and risk assessment improve, greater accuracy will be achieved in predicting health outcomes.”

Besides the monthly article and podcast series, the legacy of JDR will be honored during a celebration at the 97thGeneral Session and Exhibition of the International Association for Dental Research, to be held in conjunction with the 48thAnnual Meeting of the American Association for Dental Research and the 43rdAnnual Meeting of the Canadian Association for Dental Research in Vancouver, British Columbia, Canada, from June 19 to 22, 2019.

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